Aren van Waarde Selected Research

rimcazole

9/2013	In vivo responses of human A375M melanoma to a σ ligand: 18F-FDG PET imaging.
11/2010	Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP)-targeted delivery of soluble TRAIL potently inhibits melanoma outgrowth in vitro and in vivo.
12/2008	Cytotoxicity of sigma-receptor ligands is associated with major changes of cellular metabolism and complete occupancy of the sigma-2 subpopulation.

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Aren van Waarde Research Topics

Disease

27	Neoplasms (Cancer) 01/2021 - 10/2003
11	Inflammation (Inflammations) 11/2021 - 10/2003
9	Glioma (Gliomas) 01/2018 - 04/2004
6	Neuroinflammatory Diseases 11/2021 - 03/2012
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 07/2020
4	Cognitive Dysfunction 01/2021 - 08/2011
3	Body Weight (Weight, Body) 03/2021 - 03/2008
2	Brain Diseases (Brain Disorder) 12/2021 - 03/2008
2	Asthma (Bronchial Asthma) 01/2021 - 01/2018
2	Epilepsy (Aura) 01/2018 - 01/2016
2	Carcinoma (Carcinomatosis) 04/2017 - 11/2012
2	Memory Disorders (Memory Loss) 06/2015 - 08/2011
2	Sleep Deprivation 06/2015 - 04/2015
2	Alzheimer Disease (Alzheimer's Disease) 10/2014 - 10/2003
2	Melanoma (Melanoma, Malignant) 09/2013 - 11/2010
2	Mood Disorders (Mood Disorder) 03/2011 - 01/2004
2	Schizophrenia (Dementia Praecox) 07/2009 - 01/2004
1	Central Nervous System Diseases (CNS Diseases) 01/2022
1	Neurobehavioral Manifestations 01/2022
1	Carcinogenesis 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Disease Progression 07/2020
1	Pathologic Processes 07/2020
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Parkinson Disease (Parkinson's Disease) 01/2020
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2018
1	Rheumatoid Arthritis 01/2018
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2018
1	Breast Neoplasms (Breast Cancer) 11/2017
1	Pneumonia (Pneumonitis) 10/2015
1	Chronic Obstructive Pulmonary Disease (COPD) 10/2015
1	Lung Neoplasms (Lung Cancer) 10/2015
1	Catalepsy 09/2015

Drug/Important Bio-Agent (IBA)

12	LigandsIBA 10/2015 - 11/2004
8	sigma Receptors (sigma Receptor)IBA 10/2015 - 11/2004
6	Pharmaceutical PreparationsIBA 01/2022 - 11/2004
6	RadiopharmaceuticalsIBA 01/2021 - 01/2006
5	Biomarkers (Surrogate Marker)IBA 07/2020 - 01/2008
5	SA 4503IBA 06/2015 - 11/2004
4	EnzymesIBA 11/2021 - 02/2012
4	Proteins (Proteins, Gene)FDA Link 03/2021 - 08/2007
4	TurpentineIBA 03/2012 - 04/2004
4	Adrenergic Receptors (Adrenergic Receptor)IBA 03/2008 - 01/2004
3	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2022 - 01/2010
3	Cholinergic Agents (Cholinergics)IBA 01/2021 - 08/2011
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 09/2013
3	Haloperidol (Haldol)FDA LinkGeneric 01/2020 - 11/2004
3	Matrix Metalloproteinases (MMPs)IBA 10/2015 - 01/2013
3	Sigma-1 ReceptorIBA 06/2015 - 08/2011
3	rimcazoleIBA 09/2013 - 12/2008
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 09/2013 - 04/2004
3	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2012 - 09/2006
3	GlucuronidaseIBA 11/2012 - 02/2012
2	ArginaseIBA 01/2021 - 07/2020
2	Amyloid (Amyloid Fibrils)IBA 01/2021 - 08/2011
2	Estrogen ReceptorsIBA 11/2017 - 04/2017
2	GenisteinIBA 11/2017 - 04/2017
2	Estradiol (Delestrogen)FDA LinkGeneric 11/2017 - 04/2017
2	2- fluoro- 6- (6- hydroxynaphthalen- 2- yl)pyridin- 3- olIBA 11/2017 - 04/2017
2	Antineoplastic Agents (Antineoplastics)IBA 10/2015 - 01/2010
2	Adenosine (Adenocard)FDA LinkGeneric 05/2014 - 08/2011
2	Propranolol (Inderal)FDA LinkGeneric 02/2014 - 03/2008
2	ProdrugsIBA 11/2012 - 02/2012
2	Serotonin (5 Hydroxytryptamine)IBA 11/2012 - 03/2011
2	NucleosidesIBA 01/2008 - 04/2004
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2008 - 10/2003
2	1- (4- 2'- fluoroethoxy- 3- methoxyphenethyl)- 4- (3- (4- fluorophenyl)propyl)piperazineIBA 01/2006 - 11/2004
1	Histamine AgonistsIBA 01/2022
1	6- ((3- cyclobutyl- 2,3,4,5- tetrahydro- 1H- 3- benzazepin- 7- yl)oxy)- N- methyl- 3- pyridinecarboxamideIBA 01/2022
1	Histamine H3 Receptors (Histamine H3 Receptor)IBA 01/2022
1	Cyclooxygenase 1IBA 11/2021
1	Oxidoreductases (Dehydrogenase)IBA 01/2021
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2021
1	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA 01/2021
1	Androgen Receptors (Androgen Receptor)IBA 01/2021
1	enzalutamideIBA 01/2021
1	SynucleinsIBA 01/2021
1	HexokinaseIBA 01/2021
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021
1	isoquinolineIBA 01/2020
1	RacloprideIBA 01/2020
1	(R)- (11C)1- (2- chlorophenyl)- N- methyl- N- (1- methylpropyl)- 3- isoquinolinecarboxamideIBA 01/2020
1	Monoclonal AntibodiesIBA 01/2018
1	Cysteine (L-Cysteine)FDA Link 01/2018
1	Methionine (L-Methionine)FDA Link 01/2018
1	Estrogens (Estrogen)FDA Link 04/2017
1	Verapamil (Calan)FDA LinkGeneric 01/2016
1	Matrix Metalloproteinase InhibitorsIBA 10/2015
1	Ion Channels (Ion Channel)IBA 10/2015
1	SmokeIBA 10/2015
1	sigma-2 receptorIBA 10/2015
1	Peptide Hydrolases (Proteases)FDA Link 10/2015
1	Dopamine (Intropin)FDA LinkGeneric 09/2015
1	Metalloproteases (Metalloproteinases)IBA 01/2015
1	DisintegrinsIBA 01/2015

Therapy/Procedure

10	Therapeutics 01/2021 - 12/2003
3	Drug Therapy (Chemotherapy) 11/2012 - 09/2006
2	Radiotherapy 01/2020 - 01/2018
2	Immunotherapy 01/2018 - 11/2010